[关键词]
[摘要]
利用生物基因组学数据库,对绵羊雌激素受体(estrogen receptor,ESR)基因进行生物信息学分析。结果表明,绵羊ESR基因含有1个1 413 bp的开放阅读框,编码470个氨基酸;ESR蛋白分子质量为53 393.85 D。ESR基因主要位于细胞核中,参与机体转录调控过程。
[Key word]
[Abstract]
This study aimed to bioinformations of sheep ESR gene . The physicochemical characteristics, structures and functions of ovine ESR were predicted and analyzed with software tools and database . Meanwhile, the phylogenetic tree of ESR and related proteins was constructed, The results shows that the ORF of ESR was 1 413 bp which encoded 470 amino acids . The sheep protein of ESR was 53 393.85 D in molecular weight . The ESR gene played an important role in transcription regulation in cell nucleus .
[中图分类号]
S826;Q57
[基金项目]
甘肃省重大科技专项(1102NKDH023)部分内容