采用生长速率法，在离体条件下测定了蛇床子素对6种植物病原真菌的室内抑制效果。结果表明，蛇床子素对供试6种植物病原真菌均有不同程度的抑制作用，其中对向日葵菌核病病菌的毒力最强，其EC50值为3.628 μg/mL，相关系数为0.942 9；对西瓜蔓枯病病菌的毒力次之，其EC50值是3.940 μg/mL，相关系数为0.992 5；对葡萄灰霉病病菌的的毒力居第3位，其EC50值为4.153 μg/mL，相关系数为0.988 8；对葡萄炭疽病、棉花枯萎病病菌的毒力也较强，其EC50值分别为5.569、4.996 μg/mL，相关系数分别为0.937 7、0.962 1；对玉米茎基腐病病菌的毒力最弱，EC50值为11.371 μg/mL。

The biological activities of osthole against six plant pathogens are analysed with growth rate method. The result shows that oathole have different biological compression effect six plant pathogens. Osthole carried the strongest toxicity against Mycosphaerlla melonis and Sclerotinia sclerotiorum， of which EC50 are 3.940 and 3.628 μg/mL， respectively. Osthole carried the secondly toxicity against Botrytis cinerea， of which EC50 is 4.153 μg/mL. The EC50 on F. oxysporum f. sp. vesinfectum and Colletortrichum gloeospriodes from osthole are 4.996 and 5.569 μg/mL. Osthole carried the weakest toxicity against Fusarium graminearum， of which EC50 is 11.371 μg/mL.

S482.2

甘肃省农业科学院科技支撑计划项目(2016GAAS08)。