治理农业害虫及其抗药性发展，探寻新的防虫杀虫靶标位点非常必要。精氨酸激酶是昆虫能量代谢的关键酶，与飞行活动、识别寄主、消化食物和生长发育等密切相关，而且由于其只存在于无脊椎动物体内而成为热点防虫靶标位点。本文综述了昆虫体内精氨酸激酶的分子和晶体结构特点、分布规律与活性、环境因子影响、精氨酸激酶调节剂，及其在害虫防治中的应用及前景。

In order to control agricultural pests and pest resistance development， the exploring of new insecticidal target sites is importantly necessary. Arginine kinase is a key functional enzyme relate to energy metabolism of insects， flight activities， identifying host， digestion， the growth and development， etc， as well， because of its exist in invertebrates merely， Arginine kinase becomes a famous pest control target. Thus， This study summarized the arginine kinase molecular and crystal structure characteristics， distribution and activity and， influences of environmental factors， regulator of arginine kinase， application in pest control and the application prospect， so as to make a steppingstone to the future study and new pesticide development with arginine kinase.

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甘肃省科技重大专项(1062NKDF021)；甘肃省科技支撑计划项目(1604NKCA063)；兰州市科技计划项目(2016-3-95)；甘肃省农业科学院农业科技创新专项(2017GAAS23)。